Clinical trials drive medical progress, but their success relies on effective patient recruitment. And recruiting patients for clinical trials is no small task. Consider these statistics: 37% of trial sites struggle with under-enrollment, 11% fail to enrol any patients, and 90% of trials need their timelines doubled to meet goals. Recruiting one patient costs an average of $6,533, with replacing a drop-out patient soaring to $19,533. Getting patient recruitment right is paramount.
In the ever-evolving world of healthcare and pharmaceuticals, researchers are constantly seeking ways to make drug development more efficient and effective. Sano’s new report, “Why are drug targets with genetic evidence twice as likely to succeed in trials?” sheds light on the use of genetic evidence to significantly increase the success rates of drugs in clinical trials, offering a glimpse into the future of personalised medicine.
Genetic data is now central to how drugs are discovered, developed, and brought to patients. For teams designing precision medicine programs, understanding where this data originates is not just a scientific question. It is a strategic one. The source, quality, and accessibility of genetic data directly shape target identification, patient stratification, and trial design decisions. This article examines the major sources of genetic data used in drug discovery, from foundational genomic databases and sequencing technologies to biobanks, population studies, and functional genomics tools.
In the world of healthcare, genetics is ushering in a new era of personalised insights that are transforming how we approach healthcare. Our latest report, “The Genetic testing landscape: A look at the modern approach and the value of sponsored programs,” offers a valuable exploration of the evolving genetic testing landscape.
In the fast-paced world of medical research, patient advocacy groups have emerged as powerful drivers of change. One critical ingredient in their recipe for success is patient registries. These tools offer a direct relationship between patients and researchers, propelling medical advancements and accelerating the search for better treatments. Our newly released whitepaper, titled "Connecting communities: Engaging patients in registries for long-term impact," shares strategies and insights for patient advocacy groups that want to create impactful patient registries.
The rapidly evolving landscape of precision medicine has opened new avenues for personalised treatments, transforming how we approach patient care. Genetic information is now pivotal in tailoring medical interventions to individual needs. However, with this innovation comes a complex web of ethical and regulatory considerations that must be carefully navigated to ensure patient safety, data privacy, and ethical conduct. Here are the key insights and lessons from a recent Sano webinar in which Sarah Howard, our Head of Quality and Regulatory, shed light on the ethical and regulatory landscapes surrounding precision medicine.
Genetics is no longer confined to research labs. It shapes how diseases are diagnosed, how therapies are developed, and how patients are identified for clinical trials. As genetic concepts become more central to healthcare, staying informed matters for professionals and curious listeners alike.
In the complex world of medical research, collaboration is key to driving innovation and progress. Sano exists to accelerate the transition to precision medicine, and in the spirit of collaboration, we’ve honed our offerings to ensure value for clients based on their specific needs. Below you’ll find seven practical ways sponsors and other researchers have worked with us to achieve their goals.
Genetic testing has become a central eligibility mechanism in modern clinical trials. As genetically stratified programs expand across rare disease and oncology, the regulatory frameworks governing how tests are validated, approved, and used are increasingly consequential for sponsors operating across multiple jurisdictions. As eligibility criteria increasingly depend on confirmed genetic variants, the regulatory requirements governing testing validity, laboratory compliance, and data handling have become a material operational consideration for sponsors designing and executing genetically stratified trials.
Genetics is reshaping the landscape of clinical research, and our latest whitepaper, "Guide: Genetics Essentials for Clinical Research Professionals," offers a concise yet comprehensive overview of this rapidly evolving field. This guide explores genetics' crucial role in drug development, discovery, and patient care.