Reports

Closing the communication gap in clinical trials: A guide for sponsors

This report examines key barriers to effective trial communication with participants, including fragmented planning, regulatory constraints, and emotional or ethical challenges. It also outlines practical strategies sponsors can use to build transparency, strengthen participant engagement, and sustain trust.

Overcoming rare disease trial hurdles: Practical strategies for sponsors

In this report, Sano Genetics’ rare disease experts share six proven strategies sponsors can use to design and run more successful trials, from building trust and flexibility into study design to using technology thoughtfully.

Ten ways to avoid protocol amendments: Designing trials right the first time

In this report, we outline ten strategies sponsors can use to design trials right the first time, from patient and site engagement to optimizing eligibility criteria.

Novel precision therapies in rare disease: From autoimmunity to metabolism

In this report, we explore recent breakthroughs, from early trial results in autoimmune conditions to genome editing successes in inborn errors of metabolism, and examine the challenges of bringing these therapies into real-world practice.

Beyond the tissue biopsy: Liquid biopsies in precision medicine

In this report, we examine the evolution of liquid biopsy, from its established role in cancer to its expanding applications across medicine, and explore how it is beginning to shape clinical development and trial design.

Why Sano: Driving scientific innovation and business value in 2025

The report highlights the successes driving precision medicine forward, the bottlenecks still holding it back, and how Sano’s approach is helping sponsors overcome these challenges.

Precision medicine strategies in neuromuscular diseases

This report explores the latest advances in gene therapy, antisense oligonucleotides, and biomarker-driven strategies across a range of NMDs. It highlights key clinical findings, approved treatments, and ongoing trials, while also addressing the limitations that remain.

Guide: Empowering clinical trial sites to drive innovation in precision medicine

This guide outlines how sponsors can empower their sites to adopt new approaches effectively, reduce operational friction, and ultimately drive more successful, patient-centered trials. 

The state of precision medicine in cardiovascular and metabolic disease

A close look at how precision medicine is reshaping the way healthcare addresses cardiovascular and metabolic conditions.

Inherited retinal disorders: A primer

An in-depth look at inherited retinal disorders (IRDs), examining the genetic and biological mechanisms behind these vision-impairing conditions that affect millions globally.

Mapping the precision medicine landscape: Regional insights and future horizons

A look at the precision medicine market across five key regions: North America, Asia Pacific, Europe, Africa, and Latin America.

Strategic pathways for integrating genetic screening into public health

An exploration of essential strategies for integrating genetic screening into public health, focusing on infrastructure, policy, and global cooperation to ensure equitable and effective implementation.

Integrating genetic data into clinical practice: A guide for healthcare providers

A guide for healthcare providers on how to effectively use genetic data into clinical settings to improve patient outcomes.

Understanding natural history studies

A primer on natural history studies and their role in drug development.

Precision from the start

An exploration of the potential of genomic screening in prenatal and neonatal care and how it can be balanced with ethical considerations to benefit families and the future of healthcare.

Scaling genomic data

An examination of the hurdles facing genomic data management, and how innovations are helping to overcome these obstacles. 

ALS insights report

An overview of ALS demographics and societal impact, insights into the genetic cause of ALS, current treatments and future prospects, and Sano's Light the Way initiative.
 

The genetics of MASH

An explanation of the genetic factors and gene-environment interactions that contribute to the development and progression of MASH.

Why are drug targets with genetic evidence twice as likely to succeed in trials?

An exploration of the power of precision medicine in drug development.

The future of clinical trials

An examination of key trends revolutionising the research process.

Parkinson's disease insights report

An overview of Parkinson's treatment options, genetic influences, and economic implications.

The genetic testing landscape

A look at the modern approach and the value of sponsored programs.

Navigating rare disease recruitment

Understanding the obstacles and mapping best practices to overcome them.

AATD insights report

A close look at AATD, including prevalence statistics, impact, potential treatment options, and genetic components.

Data security and privacy considerations for the biotech industry

Why privacy-first, security-led software engineering is key. 

DNA testing guide for Parkinson's

A comprehensive overview of the genetic underpinnings of Parkinson’s disease, and how to test for it.

Multiple sclerosis insights report

An explanation of the complexities of MS, including genetic factors and an exclusive look at Sano's MS community.

Measuring and optimising clinical trials based on data

How data-driven methodologies can enhance your research endeavours, empowering you to make informed decisions for impact. 

At-home saliva samples vs. at-site blood draws

A comparison of different methods of collecting genetic data.

Long COVID insights report

The ethical and legal framework for a Genomics England and Sano Genetics participant engagement platform