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Clinical research blog

Explore our blog for insights into the big questions in precision medicine and clinical research.

From fragmentation to fusion: How AI is unlocking the value of multi-omic data in drug discovery

In drug discovery, data is the key to success. Although more and more large-scale data is being generated every year, much of it is inaccessible or fragmented. ...
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Scaling the promise of gene editing: Why progress still falls short of potential

Gene editing has progressed significantly over the past decade, evolving from an experimental technology that was associated with safety and efficacy limitation...
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Podcast recap: Chris Hopkins on developing a one-time cell therapy for Fabry disease

On this episode of The Genetics Podcast, Patrick spoke with Chris Hopkins, CEO of Glafabra Therapeutics, a company developing a one-time autologous cell therapy...
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Innovation in AAV: Breaking through bottlenecks in yield, safety, and cost

At this year’s European Society of Gene & Cell Therapy (ESGCT) meeting, one theme resonated across sessions: adeno-associated viruses (AAVs) are entering a ...
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Podcast recap: Jonathan Marchini on scaling statistical genetics from HapMap to millions of exomes

On the latest episode of The Genetics Podcast, Patrick sat down with Jonathan Marchini, Head of Statistical Genetics & Machine Learning at the Regeneron Gen...
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Podcast recap: Max Bronstein on the intersection of biotech and policy

On the latest episode of The Genetics Podcast, Patrick speaks with Max Bronstein, founder and CEO of Aviva Strategies, a health policy firm dedicated to support...
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Podcast recap: Richard Wilson on the current state of gene therapy

In this week’s episode of The Genetics Podcast, we spoke with Richard Wilson, Senior Vice President and Primary Focus Lead for Genetic Regulation at Astellas, a...
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The N-of-1 revolution: What ASOs mean for rare disease families

In rare disease, families are often forced into roles that extend far beyond caregiving. When faced with diseases for which no treatment exists, parents have of...
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Podcast recap: Celebrating 200 episodes with Patrick Short

Last week marked a major milestone for The Genetics Podcast: our 200th episode. To celebrate, host Patrick Short revisited some of the most impactful conversati...
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Clinical trial recruitment strategies for biotechs

After a decade of strong investment, the biotech sector in 2025 is navigating a markedly constrained funding environment. Early-stage companies, particularly th...
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