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Clinical research blog

Explore our blog for insights into the big questions in precision medicine and clinical research.

New study data shows a better way to find patients with liver disease and what it means for clinical trials

Finding patients who qualify for a clinical trial has always been one of the hardest parts of running one. In liver disease, particularly MASLD, it is especiall...
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Podcast recap: Vincent Dion on hijacking DNA repair machinery to treat Huntington's disease

More than three decades after the Huntington's disease gene was cloned in 1993, there is still no approved therapy that alters the course of the disease. Recent...
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Reducing screen failure starts with better trial design

When a clinical trial misses its enrollment targets, the instinct is often to look at recruitment through more channels, more outreach, and a bigger advertising...
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Podcast recap: Paul Valdmanis on long-read sequencing and the genetics of neurodegeneration

In the most recent episode of The Genetics Podcast, host Patrick Short speaks with Dr. Paul Valdmanis, Associate Professor at the University of Washington, abou...
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What four episodes of The Genetics Podcast reveal about the future of Alzheimer’s precision medicine

Alzheimer’s research is entering a new phase. For decades, the field has been shaped by the biology of amyloid plaques and tau tangles. Those remain central to ...
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Podcast recap: Sarah Marzi on how genetics, environment, and cell state shape neurodegenerative disease

In the most recent episode of The Genetics Podcast, Patrick Short speaks with Dr. Sarah Marzi, Senior Lecturer at King’s College London and Group Leader at the ...
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The long game: Precision trials shouldn’t start from zero every time

Precision medicine sponsors invest heavily to identify, educate, screen, consent, genotype, and support rare patients. In many programs, once a trial ends, that...
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Trust is the foundation of precision medicine

UK Biobank and similar resources have made an extraordinary contribution to biomedical research, enabling important advances across genomics, population health,...
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How Sano enables precision patient finding at scale

Recruitment in precision medicine and rare disease trials remains constrained by fragmented data, low prevalence populations, and heavy reliance on site-based p...
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Podcast recap: Suzanne Schindler on Alzheimer’s biomarkers

On the latest episode of The Genetics Podcast, Patrick Short speaks with Dr. Suzanne Schindler associate professor of neurology at Washington University in St. ...
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