Clinical research blog
Explore our blog for insights into the big questions in precision medicine and clinical research.
This webinar, hosted by Sano Genetics and featuring representatives from Newcastle University, Congenica, UK CRC Tissue Directory and Co-ordination Centre and Sano Genetics, focussed on the topic of diversity in clinical trials. The speakers discussed how to promote diversity in research participation, the importance of patient engagement and involvement, and how to flag potential issues earlier in the research process.
This webinar was hosted by Sano Genetics' scientific advisor, Paul Wicks, and featured representatives from Genomics England as well as Sage Bionetworks. The discussion centered around experiences and insights on patient engagement in precision medicine research, including how patients can be more involved in this type of research, as well as how design systems can impact engagement.
- Sano raises $11 million in Series A funding round led by MMC Ventures
- New funding will support the team to grow and further its mission to accelerate personalised medicine research
- Sano aims to address the challenge of a decades-long, costly drug development process so that new treatments can reach patients faster
- Sano Genetics supports personalised medicine research by increasing participation in clinical trials and guiding patients through the process
- Half of clinical trials are delayed due to recruitment issues and 85% fail as they can’t retain enough participants
- Seed round will fund free at-home DNA testing kits for 3,000 people affected by Long Covid, further development of its tech platform and team expansion
Recognising the true value of patient experience is vital for successful studies and future research engagement.
DNA testing is on the rise, with companies like Ancestry DNA, My Heritage, and 23andme all making direct-to-consumer genetic testing more accessible. But there are a few different kinds of tests out on the market and they all offer different results. If you’re looking into a rare condition, whole genome sequencing might be necessary, but if you’re just looking into your ancestry or for general health insights, exome sequencing is likely to be all you’ll need. Read on to discover the differences between the tests and their uses.
Advances in large-scale genome sequencing, data storage, and analysis, combined with extensive scientific research, are accelerating the development of personalised medicine and disease prevention. These advancements are already helping to improve outcomes for patients with chronic diseases such as coronary artery disease and breast cancer. But one of the most prevalent conditions is depression, a debilitating mental illness ranked by the World Health Organization as the leading cause of worldwide disability which impacts approximately one in six people during their lifetime. In this blog, we explore the latest research in genetic causes of depression, and whether precision medicine in this area is on the horizon.
With the exponential growth of genomic data and analysis techniques we are seeing huge breakthroughs in use of polygenic risk scores to predict genetic risk of many common diseases, such as cancer, heart disease and diabetes. The study of genetic risk for common diseases is complex, as many genetic and environmental variants affect the disease risk. But following the success of genome-wide association studies (GWAS) in identifying the causal variants associated with the disease, polygenic risk scores (PRS) provide a way of aggregating all the variants carried by an individual into a single risk score.
There is huge potential for genomics to improve effectiveness and lower costs in healthcare. The reduction in sequencing costs and the availability of tools to securely store, process, and analyse large-scale data is accelerating research in genomics, and fueling progress. One area within this field with the fastest growth and greatest potential is the incorporation of genetic testing into clinical trials.