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Clinical research blog

Explore our blog for insights into the big questions in precision medicine and clinical research.

How Sano enables precision patient finding at scale

Recruitment in precision medicine and rare disease trials remains constrained by fragmented data, low prevalence populations, and heavy reliance on site-based p...
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Genetic literacy: Prevent drop-off in trial recruitment

In rare disease and genetically stratified trials, recruitment often depends on a single critical step: confirming that a patient carries the relevant genetic v...
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Rare disease drug development requires designing for access from day one

Rare disease innovation has accelerated in recent years, particularly in cell and gene therapy (CGT). Yet for drug developers, one challenge remains persistent:...
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From click to randomization: What truly predicts trial success?

Digital recruitment has become a standard part of clinical trial execution. Sponsors invest heavily in online outreach, patient referrals, and awareness campaig...
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Understanding the gap between feasibility estimates and patient availability

Patient availability is often overestimated during trial planning. This usually starts at feasibility, where sites are asked to report how many patients they ha...
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Closing the communication gap: A sponsor’s guide to building patient trust and retention

Participation in clinical trials can be burdensome and disruptive. In addition to practical inconveniences and discomfort, participants may have to take time of...
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Expediting study start-up: Best practices for sponsors

Study start-up is a critical stage of the drug development process and can have a major impact on trial timelines, budgets, and overall success. Start-up activi...
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Built for modern trials: How Sano supports advanced genomic therapies

The next generation of advanced therapies, particularly gene therapies, hold enormous promise for patients with rare conditions. However, their clinical develop...
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Case study: Accelerating recruitment for a gene therapy trial

In recent years, the therapeutic landscape for genetic hearing loss (GHL) has advanced rapidly, with several programs reaching clinical development. However, tr...
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When systems align: Boosting site engagement through smart integration

Site disengagement can be a major barrier to successful and timely trial execution. A significant contributor to disengagement is overloading sites with redunda...
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