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Clinical research blog

Explore our blog for insights into the big questions in precision medicine and clinical research.

Next-generation genetic therapies: AAV, RNA medicines, and CRISPR

Genetic medicines have been advancing at an extraordinary pace. Following the first wave of adeno-associated virus (AAV)–based gene therapies, the toolbox for g...
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Podcast recap: Richard Wilson on the current state of gene therapy

In this week’s episode of The Genetics Podcast, we spoke with Richard Wilson, Senior Vice President and Primary Focus Lead for Genetic Regulation at Astellas, a...
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Decentralized clinical trials: At-home patient screening

Precision medicine trials increasingly depend on genetic or biomarker testing to determine eligibility. Each additional test introduces operational complexity: ...
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The N-of-1 revolution: What ASOs mean for rare disease families

In rare disease, families are often forced into roles that extend far beyond caregiving. When faced with diseases for which no treatment exists, parents have of...
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Podcast recap: Celebrating 200 episodes with Patrick Short

Last week marked a major milestone for The Genetics Podcast: our 200th episode. To celebrate, host Patrick Short revisited some of the most impactful conversati...
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Podcast recap: Xin Jin on decoding brain disorders with in vivo Perturb-seq

In the last episode of the Genetics Podcast, Patrick speaks with Dr. Xin Jin, a pioneering neuroscientist at Scripps Research, about her team’s cutting-edge met...
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Clinical trial recruitment strategies for biotechs

After a decade of strong investment, the biotech sector in 2025 is navigating a markedly constrained funding environment. Early-stage companies, particularly th...
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Podcast recap: Benny Sorenson on patient-centered drug development for clotting disorders

In the latest episode of The Genetics Podcast, we sat down with Dr. Benny Sorenson, CEO of Hemab Therapeutics, to explore a relatively overlooked therapeutic ar...
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Top five scientific trends shaping precision medicine in 2025

The promise of precision medicine has been intensifying over the past decade. In 2025, the field appears to be at an inflection point due to a confluence of var...
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Podcast recap: Heiko Runz on population genomics and drug discovery

In the latest episode of The Genetics Podcast, we spoke with Dr. Heiko Runz, SVP of Neuroscience at insitro. With a background spanning clinical genetics, acade...
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