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Clinical research blog

Explore our blog for insights into the big questions in precision medicine and clinical research.

What four episodes of The Genetics Podcast reveal about the future of Alzheimer’s precision medicine

Alzheimer’s research is entering a new phase. For decades, the field has been shaped by the biology of amyloid plaques and tau tangles. Those remain central to ...
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The long game: Precision trials shouldn’t start from zero every time

Precision medicine sponsors invest heavily to identify, educate, screen, consent, genotype, and support rare patients. In many programs, once a trial ends, that...
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Trust is the foundation of precision medicine

UK Biobank and similar resources have made an extraordinary contribution to biomedical research, enabling important advances across genomics, population health,...
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How Sano enables precision patient finding at scale

Recruitment in precision medicine and rare disease trials remains constrained by fragmented data, low prevalence populations, and heavy reliance on site-based p...
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The rare disease blueprint: What precision medicine can learn from the hardest trials

Rare disease exposes the limits of current clinical development models. Small, fragmented populations make patient identification difficult. Heterogeneous biolo...
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The forces shaping regulatory expectations in genomics-driven pharma

Regulatory expectations in genomics-driven drug development are evolving alongside scientific practice, clinical implementation, and policy. While formal guidan...
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Lessons from recent FDA actions in precision medicine 

Over the past few years, several cell and gene therapies (CGTs) in precision medicine have received FDA Complete Response Letters (CRLs). As the agency increase...
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Podcast recap: Rachel Salzman on vectorized RNAi for neuromuscular disease

In the last episode of The Genetics Podcast, Patrick spoke with Dr. Rachel Salzman, CEO of Armatus Bio, a biotech company developing vectorized RNA interference...
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Psychiatric precision medicine: What’s actually changed for trials in 2025

Psychiatric precision medicine has been a promising area of research for nearly two decades, but only recently has data emerged that can influence real clinical...
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Behind the scenes at Sano: Building the infrastructure that powers precision medicine

At Sano, every product, pipeline, and participant experience depends on secure, reliable, and scalable infrastructure. That foundation is shaped by our platform...
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