Most patients with a suspected genetic condition still move through testing one layer at a time. A panel checks a set of genes, a separate assay looks for a rep...
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In the latest episode of The Genetics Podcast, Patrick Short sits down with Dr. Brent Richards, CEO and founder of 5 Prime Sciences and Professor of Human Genet...
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In the latest episode of The Genetics Podcast, Patrick Short speaks with Dr. Andrew Jackson, Programme Leader at the MRC Human Genetics Unit within the Universi...
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Rare and ultra-rare disease research has produced real scientific breakthroughs over the past decade: antisense oligonucleotides, gene therapies, and gene editi...
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In genetic medicine, we increasingly know what to deliver. The unsolved problem is getting it to the right place in the body. That was the central thesis in the...
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Most people with inflammatory bowel disease do not carry one broken gene. They carry risk spread across many genes and regulatory regions at once, which is why ...
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Most people accumulate cancer-associated blood mutations as they age, and quietly, without ever developing cancer. A growing body of evidence now links those mu...
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For decades, the dominant framework for understanding neurodegenerative disease has centered on inherited risk genes. A growing body of single-cell genomics res...
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The C9orf72 hexanucleotide repeat expansion is the most common genetic cause of both ALS and frontotemporal dementia (FTD). Carriers face roughly a 50% chance o...
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When Trace Neuroscience announced on June 22 that first patients had been dosed in the LAUNCH ALS trial, it felt like the right moment to revisit our original p...
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