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Clinical research blog

Explore our blog for insights into the big questions in precision medicine and clinical research.

Genetic testing in precision medicine trials

Genetic testing has become a defining capability in biotechnology and pharmaceutical development. By revealing the specific genetic variants that influence dise...
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The genetic crystal ball: How polygenic risk scores predict disease risk and guide drug discovery

While lifestyle choices and environment can impact risk, genes are often what most affect how likely a person is to develop a disease. People commonly have diff...
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CRISPR gene editing: Promise, risks, and regulation

CRISPR (clustered regularly interspaced short palindromic repeats) and CRISPR-associated (Cas) proteins were first characterized as part of bacterial immune def...
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Pharmacogenomics testing: Safer dosing and reduced ADR risk

Pharmacogenomics, also known as pharmacogenetics, is a field of research dedicated to investigating how an individual's genetic makeup influences their response...
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Can ALS be Caught Early: Unravelling the Detection of ALS

In this blog, we're exploring whether ALS can be caught early, including the tests that may be used in order to diagnose ALS, and if there are any measures that...
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Drug target discovery: Genetic data to clinical trials

The success of any precision medicine program depends on the quality of the target it pursues. A well-validated genetic target shapes everything downstream: whi...
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VUS genetics in clinical trials: Managing uncertainty

When an individual undergoes genetic testing, they often expect to find definitive answers about their genes. However, around 20% of genetic tests identify vari...
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Genetic data sources for drug discovery teams

Genetic data is now central to how drugs are discovered, developed, and brought to patients. For teams designing precision medicine programs, understanding wher...
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Understanding the modern genetic testing landscape

In the world of healthcare, genetics is ushering in a new era of personalised insights that are transforming how we approach healthcare. Our latest report, “The...
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Eight genetics podcasts to follow for DNA and genomics

Genetics is no longer confined to research labs. It shapes how diseases are diagnosed, how therapies are developed, and how patients are identified for clinical...
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