A growing category of patient engagement solutions has emerged to address these challenges. The most effective approaches combine digital health platforms, personalized communications, educational content, and behavioral design to keep patients informed and motivated throughout the research journey. Below, we look at twelve companies offering patient engagement solutions relevant to clinical trial retention.
These solutions span several categories of clinical trial engagement, including:
- Digital trial platforms that integrate engagement into decentralized or hybrid study workflows
- Behavioral and gamification tools that use behavioral science to sustain motivation and adherence
- Patient education and communication platforms that deliver tailored content and support throughout the study
- Data and analytics platforms that capture patient experience and feedback to inform engagement strategy
Patient engagement solutions providers for precision trials
- Sano Genetics is a precision patient platform that unifies recruitment, genetic testing, and long-term engagement for precision medicine trials. Its engagement capabilities include tailored communications, educational content, return-of-results pathways, pulse surveys, participant dashboards, and recontact workflows. These are designed to maintain trusted participant relationships during and between study phases, addressing the extended timelines and complex eligibility processes common in genetically stratified and rare disease research.
- ObvioHealth's patient engagement offering, the ObviGo app, is a digital platform through which patients can ask questions, access on-demand videos, share health data, play engagement games, and connect with a human coach on demand.
- DataCubed is an eClinical technology company with a patient engagement platform rooted in behavioural science. They designed their platform to engage patients and promote interaction continuously, and report improved patient retention across their studies.
- Reverba is a patient engagement solutions company that combines deep relationships, technology, and a focus on privacy and security. They’ve created CareConcierge to connect patients with information and education throughout the drug development and commercialization process.
- Embleema is a blockchain-based platform which allows patients to consolidate their electronic medical records, track their health, take surveys, and share reports with physicians. They provide continuous feedback for patients and offer personalized services.
- BBK Worldwide is a clinical trial marketing and patient recruitment firm that offers a patient engagement platform designed to connect patients with clinical trials and provide ongoing support throughout the study. Their patient engagement offerings include visit-by-visit guides, educational resources and videos, and gamification.
- CareClinic is a patient engagement platform that focuses on chronic disease management and medication adherence. Patients can organise appointments, track medications and symptoms, and access educational content, all in one place.
- Cognitant is a digital health company that provides patient education and engagement tools for clinical research. They deliver effective patient engagement solutions that improve the patient experience and outcomes across the product lifecycle, from clinical trials to marketed products.
- Clinpal is an end-to-end clinical research platform built for virtual, hybrid, and direct-to-patient studies. Within its modules, it provides education and engagement for patients through text, email, and internal messaging.
- Medidata is a clinical trial management system that provides end-to-end solutions for clinical research. The Patient Cloud is a single destination patient portal that captures the patient experience in clinical trials and gathers direct patient feedback.
- SnapIoT is a provider of mobile-connected self-service platform solutions for clinical trials. Sponsors can tailor their mobile app with notifications, reminders, and gamification to drive engagement and retention.
- Alira Health provides tailored education, communication, and support through their platform to help patients navigate complex healthcare journeys and support patients in completing trial participation by providing structured education, clear communication, and logistical assistance at key decision points.
The impact of technology on clinical trial retention
Patient engagement is not a single tool or feature. It is an operational discipline that spans the full participant journey, from initial awareness through screening, enrollment, active participation, and long-term follow-up. The solutions listed above represent different approaches to this challenge, each addressing specific moments where disengagement is most likely.
In precision medicine, the stakes are higher. Smaller patient populations, longer screening pathways, and genetic eligibility requirements mean that every participant who disengages has a disproportionate impact on enrollment timelines and data quality. Effective engagement in this context requires more than reminders and educational content. It requires a coordinated system that maintains trust and connection across the full study lifecycle.
For teams running precision medicine registries, natural history studies, or genetically stratified trials, participant engagement is a structural requirement rather than an optional enhancement. Sano's platform supports this through tailored communications, educational content, return-of-results pathways, and recontact workflows, all designed to maintain participant connection across study phases and beyond.
Contact our team to discuss how Sano's platform supports participant retention in your study.