01 May 2021 - 31 Jul 2021

ZF874 Clinical Trial

  • Referral study
  • Sponsored
  • Ethically approved
  • Commercial study
  • Study site visit necessary
  • Data transferred outside Sano
  • Clinical Trial
  • DNA data required


Help contribute to the development of a potential new treatment for a rare disease called alpha-1-antitrypsin deficiency. The study is recruiting volunteers who have a genotype with at least one Z alpha-1-antitrypsin allele (PiXZ).

Interested in this study? Great! We just need to check a few things so we can let you know if you are eligible.

Participants need to:

  • Be 18 or older
  • Have uploaded DNA data to the Sano site
  • Be living in UK or United Kingdom

How to join the study

  • Log in or Sign up and complete your user profile so we have some basic information to determine if this study is relevant for you.

  • Upload your DNA data to the Sano site. Then if you decide you would like us to, as part of the pre-screen survey we can check to see if you have the genetic variants which would make you eligible for this study.

  • Answer a few quick questions to check if you are eligible and let us know that you're happy for us to pass your data on to the study team.

to participate in this study

Frequent Questions

If you have a question that is not covered here, please let us know - we’ll be happy to answer and to update these FAQs.